
Do not be shocked! World Health Organization (WHO) reveals that 91% of people in the world live in poor air quality which exceeds its safety limits. That’s why you are reading this best HEPA air purifier review.
As its name suggests, the purifier keeps the air clean by filtering the airborne pollutants such as leads, cigarettes, or arsenic. You can expect the air to be fresher so that your allergy or respiratory problems will go in a flash.
Scroll down to know more about the HEPA technology, why it has become so popular, and more importantly, which is the best HEPA air purifier for your beloved family.
Top-Rated Comparison Chart
Pure Enrichment PureZone 3-in-1 | Honeywell 50250-S | Winix 5500-2 Air Purifier | Germ Guardian AC4825 | RabbitAir MinusA2 Ultra Quiet | |
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Image | ![]() | ![]() | ![]() | ![]() | ![]() |
Size | 10.8 x 6.9 x 12.1 in | 18 x 18 x 19 in | 15 x 8.2 x 23.6 in | 9 x 5.5 x 21.5 in | 24.1 x 23 x 9.8 in |
Power | 120V, 50Hz, 60W | 120V, 50Hz, 80-190W | 120V, 50Hz, 70W | 120V, 50Hz, 60W | 120V, 50Hz, 47W |
Coverage Area | 200 sq ft | 390 sq. ft | 360 square ft | 167 sq.ft | 815 sq. ft |
Noise | 30 - 50 dB | 35-57 dB | 28-58dB | 55db | 20.8-45.6dB |
Advanced Features | Auto-shutdown to save energy | 360-degree air intake and output | Auto mode & smart sensors | 3-in-1 filtration process | Customized filters and panel |
Here are the Best HEPA Air Purifiers:
1. Pure Enrichment PureZone Air Purifier – 3 Stage Filtration

Pure Enrichment is the leading company in manufacturing air purifiers, hence, it stands for high-quality products which meet all safety protocols. This PureZone 3-in-1 is no exception. It is even the best HEPA air purifier 2022.
Helpfully, the built-in 3-stage purification ensures the air to be both clean and odor-free.
The first active carbon pre-filter removes all damp smell in the air. Secondly, the true HEPA filter catches out 99.97% airborne particles larger than 0.3 microns. The last UV-C light is designed to destroy micro-objects like germs, viruses, fungi, and bacteria. Your household air will be clean at all time.
The light supports a 254-nm wavelength and 20000 working hours so you can expect it to last for a year. However, the light is so small that you might wonder whether it can kill all dangerous contaminants. Anyway, better safe than sorry.
The smart operation is another plus. You can set the air purifier to turn off automatically every 2, 4, or 8 hours. Besides saving energy, this also protects the machine from overworking.
In addition, the PureZone 3-in-1 is a quiet HEPA air purifier. You can choose the noise level from 30dB to 50dB. The fan speed is adjusted accordingly to meet with your purposes.
However, please note that the coverage area is only up to 200 square feet – it is not wide enough for your big living room.
Due to its limited coverage capacity, I recommend the Pure Enrichment PureZon as the best true HEPA air purifier for your bedroom or kitchen. This drawback aside, all features are beyond the standards considering the price range.
2. Honeywell 50250-S True HEPA Air Purifier, 390 sq. ft, White

Every pollen season, children are often prone to serious allergies. But no worries if you buy this Honeywell 50250-S for the living room. This purifier is built with your respiratory problems and allergies in mind.
Using 3 air-filtration stages, this air purifier is excellent in removing up to 99.97% of microscopic pollen, dust, mold, pet dander, and smoke – the most common causes of allergies.
The first carbon pre-filter is designed to capture large dust bunnies and pet hair. It both remove bad odors from your air and lengthens the lifespan of the second true HEPA filter, which deals with 0.3-micron-and-less objects.
Even better, the filter has a cylinder shape to distribute clean air to all directions. The coverage is nearly 390 sq. ft. You can call this Honeywell 50250-S a whole house HEPA air purifier to protect your children from allergy pollutants.
Now let’s discuss the operation. The overall structure seems a bit old compared to other counterparts. All buttons are on the top of the unit. And, you have to switch manually to change the fan speed. But good news – the purifier is effortless to operate. You do not need to remember all complicated auto modes.
And be aware that this is not a quiet HEPA air purifier! The 360-degree fan is powerful to scatter the air to all corners. However, it is a bit noisy in the dead of night. As long as you do not put it in the bedroom, it is still acceptable.
This air purifier is the best performer to remove the allergy particles, especially when your room is large or even extra-large.
3. Winix 5500-2 Air Purifier with True HEPA

Those looking for a small and quiet HEPA air purifier for bedrooms or playing rooms, look no further. This Winix 5500-2 excellently fits your demand.
The units come at 15 x 8.2 x 23.6 inches in size – not the smallest HEPA purifier in the market. However, it is still compact to transport and place here and there at will. Most importantly, the purifier is the best regarding the air-filtration quality and user-friendly operation.
Like other names in the list, it can remove almost all unwanted contaminants as small as 0.3 microns through 3 stages.
The first AOC carbon filter reduces the common odors. The True HEPA filter captures tiny particles. And, the best part is the PlasmaWave ionizer. It forms hydroxyl radicals to attack with stubborn pollutants like bacteria, viruses, chemical gases, and germs.
Additionally, both manual and automatic modes are well-performed. You can switch among 4 fan speeds to maximize the airflow or to save on energy consumption. The Low, Medium and Sleep mode are nearly silent so you can fall deep into sleep at the very night.
Otherwise, let the smart sensors take all care. Once you turn on the auto mode, the sensors work immediately to adjust the fan speed based on the air quality around.
Sadly, some users complain that this 5500-2 version does not remove all bad smell like its brothers. say Winix WAC9500.
Of all small-sized HEPA air purifier, the Winix 5500-2 is a good choice due to its powerful filtration and useful additional features.
4. Germ Guardian AC4825E True HEPA Filter Air Purifier

If your indoor air is of average quality, and you just want a basic HEPA air purifier for mold and other common airborne particles, this Germ Guardian AC4825 completes the job very well.
Not only is the unit affordable, but the regular replacement cost is also low. While many HEPA air purifiers require to change the filters every 3 months, those of the Germ Guardian AC4825 can last up to 8 months. The lifespan of the UV-C bulb is often from 10 to 12 months.
Though the purifier is as small as 22 inch in size, it can handle medium-to-large rooms of 167 sq. feet.
The air filtration quality is certified by CADR and AHAM verifications. Besides the activated charcoal pre-filter and true HEPA filter, there is a titanium-dioxide UL-C light to kill all remaining germs, mold spores, and viruses.
The quiet operation is another plus. At the maximum operation, the AC4825 only produces the noise level at around 55db. It is much quieter than the counterparts at the price category.
Without too many bells and whistles, this unit will also save on your budget. However, do not expect smart features like auto mode or sensors.
Despite the compact size (only 7lbs in weight), this budget HEPA air purifier is powerful enough to take care of medium to large spaces.
5. RabbitAir MinusA2 Ultra Quiet HEPA Air Purifier

All earlier HEPA air purifiers have excellent performances; however, the coverage area is somewhat limited. If your room is extra large, take this RabbitAir MinusA2 instead. It is a top-notch purifier with lots of extra features.
The filtration system is powerful and the room coverage area is up to 815 sq.ft.
While others have only two or three filters, the MinusA2 has 6 filters, one of which is customizable based on your own needs. Such flexibility improves air quality and saves on energy consumption.
The first pre-filter prevents large particles from bypassing the air flow. The second medium filter will capture the mold, pet dander, and pollen. Advanced BioGS HEPA filter is more advanced than the True HEPA filter to optimize the filtration efficiency. Customized filter (Germ defense, odor remover, pet allergy, and toxin absorber), the carbon filter and ion generator add an extra clean to the air.
More excitingly, the unit can stand alone or be attached on the wall thanks to its lightweight and flexible design.
If there is one thing to improve, the manufacturer should adopt wifi-function of the premium RabbitAir MinusA2 SPA-780N. More advanced, more fun.
This is the top whole house whole house HEPA air purifier which is both powerful and feature-rich. Overall, worth every penny!
Why Are HEPA Air Purifiers Recommended?
What Is HEPA Filtration?
Standing for High-Efficiency Particulate Air, the true HEPA is a filtering technology certified by the Institute of Environmental Sciences and Technology. It guarantees to remove 99.97% of particulates as small as 0.3 microns. Some HEPA air purifier can even trap particles which is smaller than 0.3 microns.
Those particles, including pet dander, dust mites, or pollens, are so ultra-microscopic that they become completely invisible to our eyes. As a result, they manage to make their way into our house and cause us to sneeze, cough or have an allergy. Even worse, we can suffer from dangerous diseases related to respiratory systems.
How Does a HEPA Air Purifier Work?

HEPA filtration unit is often made of multiple fibers, to be exact, the glass fiber or polypropylene non-woven fabrics.
They are in place to prevent almost all particles from traveling through the fibers and get into your air. Those filter fibers are held together in a cardboard or plastic frame in order to prevent air from passing by the purifier.
Based on the size of pollutants, the filtration can proceed by different methods: interception, impact, and diffusion.
- Interception works with medium-sized particles, which are often larger than 0.4 microns.
- Inertial impaction will catch larger contaminants attempting to get through the fiber media.
- Whereas, diffusion will dissipate the particles as small as 0.3 to 0.1 microns. Consequently, almost no pollutants have chances to get around and spell sickness on you.
Due to such the deep filtering quality, HEPA filters need replacing frequently. If the air quality is average, the unit can last up to 1 year. Otherwise, you should change the filters every 6 months.
Benefits of HEPA Technology
1. HEPA fibers deal with tiny particles very well
With three filtering modes, you can expect the best HEPA air purifier to deal with micron pollutants which the regular vacuum cannot remove.
2. It eases your asthma or allergies
HEPA air purifier removes almost all tiny airborne particles which cause breathing problems right from the start. Hence, you can enjoy fresh and pollutant-free airflow.
Say goodbye to the annoying sneezes and wheezes every season of pollen!
3. Moreover, HEPA fibers work even better over time
Many tests have demonstrated that the dirtier they become, the higher amount of particles the fibers can deal with.
Some advanced HEPA air purifiers are even washable. This adds extra durability to the filters and decreases the replacement cost.
4. The best HEPA air purifiers machines often come with pre-filters
Pre-filters, say, the active carbon filters can catch bigger pollutants that make your HEPA units become dirty quickly.
It protects your purifier and your wallet as well.
5. HEPA technology does not create ozone
It becomes a standard for most HEPA machines that they must be at a safe ozone level. It means you not only protect your family’s health but you also protect our Earth.
The Last Verdict
You must buy one of these best HEPA air purifier machines to take better care of your beloved family.
In case you still do not know what to choose, we strongly recommend the Pure Enrichment PureZon. The filtration performance is excellent with 3 stages. The operation is almost silent. And, the price is surprisingly affordable!